Summary of Collaborative Work with Infectious Disease Division

• Project leader: Tim Sterling

• Investigators: Todd Hulgan, Tim Sterling
• Completed Work:
  • Analysis looking at predictive power of CD4% for time until AIDS defining event or death.
  • Abstract submitted to CROI
• Next Task:
  • Better understand association of CD4% -- particularly study interaction of CD4% and aCD4

• Investigators: Diana Lemley, Steve Raffanti
• Completed Work:
  • Multivariable logistic regression analysis
  • Abstract submitted to CROI
• Next Task:
  • Diana and Steve are working on draft of manuscript
  • An analysis that accounts for missing data?

• Jennifer Tai (OC3 project)
• Gema Barkanic (substance abuse project)

• Study design for methods to reduce the rate of false positive contaminant blood cultures:
  • Randomized block design
• Analysis plan for interrupted time series design:
  • Poisson regression with # cathedar days of risk as offset, adjusting for new treatment, time using splines, interaction of time and treatment, and assuming AR(1) correlation structure

• Investigators: Daniel Masys, Richard d'Aquila, and others
• Completed Work:
  • General description of analyses
  • Statistical Methods section of grant: sensitivity analyses and incorporating sampling weights into phylogenetic analysis

• Investigators: Wonder Drake
• Completed Work:
  • Basic comparisons using Fisher's Exact Test, Chi-square tests, and Kruskal-Wallis
  • Two abstracts submitted

• Lora Thomas:
  • Review of journal club article where Frank was wrongly acknowledged