Vanderbilt University School of Medicine Department of Biostatistics 2525 West End Ste. 11000 Nashville, TN 37203
Education
PhD in Statistics, Case Western Reserve University, Cleveland, OH
BS, Univeristy of Science and Technology of China, Hefei, Anhui, China
Selected Publications
Johnson DB, Balko JM, Compton ML, Chalkias S, Gorham J, Xu Y, Hicks M, Puzanov I, Alexander MR, Bloomer TL, Becker JR, Slosky DA, Phillips EJ, Pilkinton MA, Craig-Owens L, Kola N, Plautz G, Reshef DS, Deutsch JS, Deering RP, Olenchock BA, Lichtman AH, Roden DM, Seidman CE, Koralnik IJ, Seidman JG, Hoffman RD, Taube JM, Diaz LA Jr, Anders RA, Sosman JA, Moslehi JJ. Fulminant Myocarditis with Combination Immune Checkpoint Blockade. _N Engl J Med_. 2016 Nov 3;375(18):1749-1755.
Bhasin JM, Lee BH, Matkin L, Taylor MG, Hu B, Xu Y, Magi-Galluzzi C, Klein EA, Ting AH. Methylome-wide Sequencing Detects DNA Hypermethylation Distinguishing Indolent from Aggressive Prostate Cancer. Cell Rep. 2015 Dec 15;13(10):2135-46. doi: 10.1016/j.celrep.2015.10.078.
Xu Y, Guo X, Sun J, Zhao Z. Snowball: resampling combined with distance-based regression to discover transcriptional consequences of a driver mutation. Bioinformatics. 2014 Jan; 1;31(1):84-93.
Xu Y, Hu B, Choi AJ, Gopalan B, Lee BH, Kalady MF, Church JM, Ting AH. Unique DNA methylome profiles in CpGisland methylator phenotype colon cancers. Genome Res. 2012 Feb;22(2):283-91. doi: 10.1101/gr.122788.111.
Beall CM, Cavalleri GL, Deng L, Elston RC, Gao Y, Knight J…Xu Y…Zheng YT. Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11459-64.
Patocs A, Zhang L, Xu Y, Weber F, Caldes T, Mutter GL, Platzer P, Eng C. Breast-cancer stromal cells with TP53 mutations and nodal metastases. N Engl J Med. 2007 Dec 20;357(25):2543-51.
Weber F, Xu Y, Zhang L, Patocs A, Shen L, Platzer P, Eng C. Microenvironmental genomic alterations and clinicopathological behavior in head and neck squamous cell carcinoma. JAMA. 2007 Jan 10;297(2):187-95.