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StatThinkingAgenda
(17 May 2006,
AyumiShintani
)
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---+ Statistical Thinking in Biomedical Research: Agenda for a Short Course or Research RetreatICUD ---+++ Goals: 1 Present the biostatistical concepts that researchers need in order to evaluate the results of published clinical studies, to design and analyze studies, and to collaborate effectively with methodologists 1 Illustrate how biostatistical and epidemiologic principles affect all phases of the study, including choosing an outcome measure, developing procedures for collecting accurate and complete data and summarizing study results 1 Introduce participants to fundamental concepts in statistical inference to be able to recognize problems of bias and imprecision that can lead to misleading or uninformative results 1 Present approaches for choosing response variables and clinical endpoints 1 Learn about levels of evidence provided by different types of studies 1 Understand underlying concepts, not computations 1 To learn about existing biostatistical resources at Vanderbilt and how to build division-specific resources ---+++ Outline 1 What does biostatistics have to offer to biomedical research? 1 Fundamentals of statistical inference 1 Study design issues 1 Sources of bias 1 Measurement issues and choice of response variable 1 Efficiency, power, and precision 1 Maximizing use of a given number of animals 1 Interpretability of findings 1 Types of studies and role of randomization 1 Pitfalls in interpreting statistical results 1 Descriptive statistics 1 Measuring change 1 Reproducible research 1 How to collaborate with biostatisticians 1 Biostatistical resources
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Topic revision: r2 - 17 May 2006,
AyumiShintani
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