Statistical Thinking in Biomedical Research: Agenda for a Short Course or Research RetreatICUD
Goals:
Present the biostatistical concepts that researchers need in order to evaluate the results of published clinical studies, to design and analyze studies, and to collaborate effectively with methodologists
Illustrate how biostatistical and epidemiologic principles affect all phases of the study, including choosing an outcome measure, developing procedures for collecting accurate and complete data and summarizing study results
Introduce participants to fundamental concepts in statistical inference to be able to recognize problems of bias and imprecision that can lead to misleading or uninformative results
Present approaches for choosing response variables and clinical endpoints
Learn about levels of evidence provided by different types of studies
Understand underlying concepts, not computations
To learn about existing biostatistical resources at Vanderbilt and how to build division-specific resources
Outline
What does biostatistics have to offer to biomedical research?
Fundamentals of statistical inference
Study design issues
Sources of bias
Measurement issues and choice of response variable