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-- Main.SvetlanaEden - 09 Nov 2010 ------------------------- ------------------------ ---------------------- ---+ Population Definitions ---++++Population One 1 Inpatient Scr greater than 2 (!InptCrCtr > 2) 1 Non-missing baseline Scr (!MostRecentPreadmitOutptCr - non-missing) 1 !DaysFirstEncounterPostDC <= 365 ---++++Population Two All patients from Population One plus 1 Days from admission to death is non-negative (!DaysDeathFromAdm>=0) 1 No preadmission dialysis appointment (!PreAdmitDialysisCtrAppt = 0) 1 !PreAdmDialysisCtrICD = 0 1 Most recent outpatient GFR >=15 (!MostRecentOutPtGFR >= 15) 1 No preadmission renal transplantations (!PreAdmit_RenalTransplant == 0 ) 1 No dialysis post peak 23 to 30 days (!PostPeak_23_30_Dialysis == 0) 1 Length of stay is 30 days or less (!LOSDays <= 30) 1 No preadmission renal appointment (!PreAdmitRenalClinicScheduledCtr == 0) 1 !LastBefore30DayPostPeakGFR < 60 1 No preadmission renal visit (!PreAdmitRenalClinicSeen == 0) 1 Non-missing !PreAdmRenalConsultCtr ---++++Analysis Population All patients from Population Two plus 1 AKI stage 1 or greater (!AKINStage >=1) 1 No discharge diagnosis of ESRD within 30 days of admission (missing !Discharge_ESRD_WI30) 1 Not a preadmission hospice patient (!PreAdmit_Hospice==0) 1 First admission (!FirstAKIAdmit = 1) ----------------------- ----------------------- ----------------------- ---+ Variable Definitions * !DaysFirst30DayPostPeakGTE60GFR - the first time after 30 days post peak in which the GFR for the patient was above or equal to 60. * take all of the creatinines for each patient after the first 30 days post peak * calculated their GFR based on the equation (race, age, gender) * filter to keep only those that were 60 or above * find the first time (in days after 30 days peak) in which that was the case * !RecoveredAfter270Days - if patient's recovery (GFR of 60 or greater) is observed at or after 270 days in the after-30-days-post-peak period. * !DaysFirst30DayPostPeakGTE60GFR >= 270 * !strataBlGFR60, two levels * "less than 60" if !MostRecentOutPtGFR<60 * "60 or more" if !MostRecentOutPtGFR >= 60 * !HundrPercServConn * date of service connection is before admission: !100SCDate < admDate * Diagnosis Variables ("CADDx", "CHFDx", "DMDx", "HTNDx", "PVDDx") * !CADDx TRUE (a person was diagnosed with CAD) if !CADDxDate was equal or before the admission date (admDate) * Variable time-to-dialysis dialysisDays * !minimum of !PostPeak30DialysisCtrCD and !PostPeak30DialysisCtrAppt ----------------------- ----------------------- ----------------------- ---+ Analysis references 1 Kalbfleisch, J.D. and Prentice, R.L.(1980) The Statistical Analysis of Failure Time Data. New York: John Wiley & Sons, Inc. 1 Robert J. Gray, A CLASS OF K-SAMPLE TESTS FOR COMPARING THE CUMULATIVE INCIDENCE OF A COMPETING RISK, The Annals of Statistics, 1988, Vol 16, No. 3, 1141-1154 1 Jason P. Fine, Robert J. Gray, A PROPORTIONAL HAZARD MODEL FOR THE SUBDISTRIBUTION OF A COMPETING RISK, Journal of the American Statistical Association, June 1999, Vol. 94, No. 446, 496-509 1 Melania Pintilie, COMPETING RISKS, A PRACTICAL PERSPECTIVE, 2006, John Wiley & Sons, Ltd. 1 Terry M. Therneau, Patricia M. Grambsch, MODELING SURVIVAL DATA, EXTENDING THE COX MODEL, 2000, Springer, New York --- <!--- TWiki Variables. Do Not Change * Set ALLOWTOPICCHANGE = Main.MichaelMatheny, Main.SvetlanaEden -->
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Topic revision: r12 - 03 Mar 2011,
SvetlanaEden
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