You are here:
Vanderbilt Biostatistics Wiki
>
Main Web
>
Seminars
>
WednesdaySeminarSeries
>
NickStrayer3April2019
(19 Mar 2019,
SrKrueger
)
(raw view)
E
dit
A
ttach
%HEAD{ NAME="Nick Strayer, !PhD" AFFILIATION="Vanderbilt University Medical Center" TITLE="Taking a network view of EHR and Biobank data to find explainable multivariate patterns" IMAGELINK="https://assets.datacamp.com/users/avatars/001/650/878/medium/nstrayer.jpg?" }% Extracting informative and meaningful results from EHR and Biobank data is an important task in genomic data science. Up to now statistically principled methods that can find robust and explainable multivariate patterns in these data have yet to take hold. Existing analysis frameworks have difficulty dealing with both the high-dimensionality of such data and also how to communicate the results in an intuitive and actionable way. In this talk I will go over some of the recent work we have done with PheWAS data that views it as a bipartite network of individual-feature relationships instead of the traditional observation and variable view; in addition we will show new visualization tools we've developed that allow collaborators to interact with these networks to interrogate genotype-phenotype associations. These methods have already been successfully deployed in real-world collaboration scenarios; furthermore, simulations of the theoretical properties of the methods have shown they are consistent and powerful in extracting multivariate patterns. By merging network-science and statistics these methods have the potential to produce more efficient and intuitive analysis tools for dealing with complex EHR and biobank data. %TAIL{DATE="3 April 2019"}% <!-- * Set HEAD = <div class="w3-card-2" id="task" style="max-width:750px; margin-left: 0px;"> <header class="w3-container w3-blue" style="padding:40px"><h1>Biostatistics Weekly Seminar</h1><br><h2 style="color:white;">%TITLE%<br><br>%NAME%<br>%AFFILIATION%</h2></header><div class="w3-container" style="padding:40px"><IMG SRC=%IMAGELINK% align="left" id="mug"/> * Set TAIL = <br><h3>MRBIII, Room 1220<br>%DATE%<br>1:30pm</h3></div></div><br>[[%TOPIC%Itinerary][Speaker Itinerary]] --> <style> .w3-card-2,.w3-example{box-shadow:0 2px 4px 0 rgba(0,0,0,0.16),0 2px 10px 0 rgba(0,0,0,0.12)!important} .w3-blue,.w3-hover-blue:hover{color:#fff!important;background-color:#2196F3!important} .w3-container{padding:0.01em 16px} .foswikiTopic {font-family: 'Open Sans', sans-serif;} /* Removes location hierarchy (usually written in grey text) */ .patternHomePath {display:none;} /* Removes bar with edit and attach buttons and location hierarchy */ .patternTop{display:none;} h1, h2, h3, h4, h5, h6{font-family: 'Montserrat','Open Sans', sans-serif;font-weight:700;} h1, h2, h3, h4, h5, h6{color:#bf1735;} h1:first-of-type{color:#2a3e6e;margin-bottom:25px;margin-top:5px;} .foswikiImage{margin-left:-9px;} img#mug{padding-right: 40px; padding-bottom:25px; height:250px;} </style>
E
dit
|
A
ttach
|
P
rint version
|
H
istory
: r5
<
r4
<
r3
<
r2
|
B
acklinks
|
V
iew topic
|
Edit
w
iki text
|
M
ore topic actions
Topic revision: r5 - 19 Mar 2019,
SrKrueger
Main
Department Home Page
Biostatistics Graduate Program
Vanderbilt University Medical Center
Main Web
Main Web Home
Search
Recent Changes
Changes
Topic list
Biostatistics Webs
Archive
Main
Sandbox
System
Register
|
Log In
Copyright © 2013-2022 by the contributing authors. All material on this collaboration platform is the property of the contributing authors.
Ideas, requests, problems regarding Vanderbilt Biostatistics Wiki?
Send feedback