You are here:
Vanderbilt Biostatistics Wiki
>
Main Web
>
Seminars
>
WednesdaySeminarSeries
>
FrankHarrellFebruary042015
(05 Feb 2015,
AshleeBartley
)
(raw view)
E
dit
A
ttach
---+++ Department of Biostatistics Seminar/Workshop Series ---+ How To Do Bad Biomarker Research ---++ Frank E. Harrell, Jr., Ph.D ---++ Professor and Chairman, Department of Biostatistics ---++ Vanderbilt University School of Medicine This talk will cover some of the bad statistical practices that have crept into biomarker research, including improper use of continuous variables, the use of improper predictive accuracy indexes, and setting the bar too low for demonstrating that biomarker information is new. Some special problems in dealing with higher-dimensional candidate biomarkers will be briefly discussed. Kidney disease poses special problems in biomarker research because commonly used definitions of kidney dysfunction/injury are based on categorizations that violate several statistical and clinical principles. This will also be discussed.
E
dit
|
A
ttach
|
P
rint version
|
H
istory
: r2
<
r1
|
B
acklinks
|
V
iew topic
|
Edit
w
iki text
|
M
ore topic actions
Topic revision: r2 - 05 Feb 2015,
AshleeBartley
Main
Department Home Page
Biostatistics Graduate Program
Vanderbilt University Medical Center
Main Web
Main Web Home
Search
Recent Changes
Changes
Topic list
Biostatistics Webs
Archive
Main
Sandbox
System
Register
|
Log In
Copyright © 2013-2022 by the contributing authors. All material on this collaboration platform is the property of the contributing authors.
Ideas, requests, problems regarding Vanderbilt Biostatistics Wiki?
Send feedback