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ElizabethOgburn20201028
(24 Sep 2020,
AndrewSpieker
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%HEAD{ NAME="Elizabeth Ogburn, !PhD" AFFILIATION="Johns Hopkins University" TITLE="Network Dependence Can Lead to Spurious Associations and Invalid Inference" IMAGELINK="https://assets.jhsph.edu/faculty/profile/230/2877.png" }% Researchers across the health and social sciences generally assume that observations are independent, even while relying on convenience samples that draw subjects from one or a small number of communities, schools, hospitals, etc. A paradigmatic example of this is the Framingham Heart Study (FHS). Many of the limitations of such samples are well-known, but the issue of statistical dependence due to social network ties has not previously been addressed. We show that, along with anticonservative variance estimation, this can result in spurious associations due to network dependence. Using a statistical test that we adapted from one developed for spatial autocorrelation, we test for network dependence in several of the thousands of influential papers that have been published using FHS data. Results suggest that some of the many decades of research on coronary heart disease, other health outcomes, and peer influence using FHS data may suffer from spurious associations, error-prone point estimates, and anticonservative inference due to unacknowledged network dependence. These issues are not unique to the FHS; as researchers in psychology, medicine, and beyond grapple with replication failures, this unacknowledged source of invalid statistical inference should be part of the conversation. %TAIL{DATE="28 October 2020"}% <!-- * Set HEAD = <div class="w3-card-2" id="task" style="max-width:750px; margin-left: 0px;"> <header class="w3-container w3-blue" style="padding:40px"><h1>Biostatistics Weekly Seminar</h1><br><h2 style="color:white;">%TITLE%<br><br>%NAME%<br>%AFFILIATION%</h2></header><div class="w3-container" style="padding:40px"><IMG SRC=%IMAGELINK% align="left" id="mug"/> * Set TAIL = <br><h3>Zoom (Link to Follow)<br>%DATE%<br>1:30pm</h3></div></div><br>[[%TOPIC%Itinerary][Speaker Itinerary]] --> <style> .w3-card-2,.w3-example{box-shadow:0 2px 4px 0 rgba(0,0,0,0.16),0 2px 10px 0 rgba(0,0,0,0.12)!important} .w3-blue,.w3-hover-blue:hover{color:#fff!important;background-color:#2196F3!important} .w3-container{padding:0.01em 16px} .foswikiTopic {font-family: 'Open Sans', sans-serif;} /* Removes location hierarchy (usually written in grey text) */ .patternHomePath {display:none;} /* Removes bar with edit and attach buttons and location hierarchy */ .patternTop{display:none;} h1, h2, h3, h4, h5, h6{font-family: 'Montserrat','Open Sans', sans-serif;font-weight:700;} h1, h2, h3, h4, h5, h6{color:#bf1735;} h1:first-of-type{color:#2a3e6e;margin-bottom:25px;margin-top:5px;} .foswikiImage{margin-left:-9px;} img#mug{padding-right: 40px; padding-bottom:25px; height:250px;} </style>
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Topic revision: r2 - 24 Sep 2020,
AndrewSpieker
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