Bosenberg, A. T. (1995) "Skin-epidural distance in children." Anaesthesia. 50: 895-897.
  • SED Data (digitized from paper figure): Bosenberg1995.csv
  • Scanned image from the Bosenberg (1995) paper: Bosenberg1995.png
  • Digitized SED figure from the Bosenberg paper (Fig. 2): Bosenberg1995.svg
  • Fitted linear regression line: SED = 3.93 + 0.80 * WT, where SED is in mm units, and WT is in kg units (R2 = 0.74).
  • From the paper:

Statistical methods: Regression analysis using the least squares procedure was used to determine the association between the skin-epidural distance and weight. For the difference between the two equations, i.e. the regression equation and the hypothesised 1 mm = 1 kg body weight, a Z-test was performed.

In children over 10 years (n = 19) there was also poor correlation. The data from these patients were not used for further analysis.

Plotting the best fit regression line and its 95% confidence limits shows that the y = x line, or skin-epidural distance (mm) is equal to weight (kg) falls within these limits for weight <40 kg (or 10 years of age) in this series (Fig. 2). Therefore the difference between any two points on these two lines is not statistically significant.

In addition a Z-test performed on any two points obtained from the two equations for a specific weight, i.e. skin-epidural distance (mm) = 0.80 weight (kg) 3.93, and skin-epidural distance (mm) = weight (kg) was found to be not statistically significant.

...

In summary, we have demonstrated that 1 mm/kg is a useful guideline for judging the skin-epidural distance in children between 6 months and 10 years of age.

Questions about the paper:
  • Was the confidence band really a prediction band?
  • Was it simultaneous or pointwise?
  • Was Bosenberg's reasoning sound?
  • How can we verify Bosenberg's conclusions?

-- MattShotwell - 16 Sep 2012

Topic attachments
I Attachment Action Size Date Who Comment
Bosenberg1995.pngpng Bosenberg1995.png manage 38.6 K 17 Sep 2012 - 07:56 MattShotwell Scanned image from the Bosenberg (1995) paper.
Bosenberg1995.svgsvg Bosenberg1995.svg manage 185.3 K 16 Sep 2012 - 10:02 MattShotwell Digitized SED data from Bosenberg (1995) paper
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Topic revision: r2 - 17 Sep 2012, MattShotwell
 

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