ATOM: Association Test via Optimally-weighted Markers
URL of this page:
http://biostat.mc.vanderbilt.edu/ATOM
This
program is written in R (
www.r-project.org). The package has four files. The analysis functions are in
ATOM.r
. The other three files provide example data and code for running ATOM.
To run ATOM, you need to prepare a reference data set for the region of interest. The example data set was extracted from the HapMap.
Please see the file
ATOM.r
for detailed explanations of the arguments of
ATOM()
.
The paper that describes the method is:
Li M, Wang K, Grant SF, Hakonarson H, Li C (2009) ATOM: A powerful gene-based association test by combining optimally weighted markers. Bioinformatics 25:497-503 (PMID: 19074959) (
paper)