Shuo Chen, M.S.

Bioinformatics System Engineer

Phone: 1-615-936-0588;
Fax:      1-615-936-2602;
Vanderbilt Ingram Cancer Center
Department of Biostatistics
571 PRB
Nashville, TN 37232-6848

  • Name: Shuo Chen
  • Title: Bioinformatics System Engineer
  • Email:
  • Phone Number: 1-615-936-0588
  • Address: 571 PRB, Vanderbilt Ingram Cancer Center, Nashville, TN. 37232-6848

Research Interests

  • High-throughput Biomedical Data Analysis.
  • Mass Spectrometry Data Analysis.
  • Machine Learning Algorithms and Application.
  • Wavelets and Splines application in Biomedical information extraction.
  • QA/QC, Reproducibility analysis, Survival analysis for of Proteomic data.


  • August 2005, Part-time Graduate student in Biomedical Informatics, Vanderbilt University.

  • December 2004, Master of Science in Mathematics and Statistics , East Tennessee State University.

  • July 2003, Bachelor of Engineering in Electrical Engineering, Harbin Institute of Technology.

Publication and Talks


1. Shuo Chen, Don Hong, and Yu Shyr, Wavelets Based Proteomic Data Processing, Statistical Computation and Data Analysis. 52 2007 211-220

2. M. Agulnik, G. da Cunha-Santos, D. Hedley, T. Nicklee, P. Pintor dos, Reis, J.Ho, G. R. Pond, H. Chen, S. Chen, Y. Shyr, E. Winquist, D. Soulieres, E. X. Chen,J. A. Squire, P. Marrano, S. Kamel-Reid, J. Dancey, L. L. Siu, M.S. Tsao Predictive and Pharmacodynamic Biomarker Studies in Tumor and Skin Tissue Samples of Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck treated by Erlotinib, by Journal of Clinical Oncology, 2007 Jun 1;25(16):2184-90.

3. Yildiz P, Shyr Y, Rahman SMJ, Wardwell NR, Zimmerman LJ, Shakhtour B,Gray WH,Li H, Chen S, Moore JH, Liebler DC, Bigbee WL, Siegfried JM, Weissfeld JL, Gonzalez AL, Ninan M, Johnson DH, Carbone DP, Caprioli RM and Massion PP Diagnostic Accuracy of MALDI Mass Spectrometric Analysis of Unfractionated Serum in Lung Cancer, Journal of Thoracic Oncology. 2(10):893-901, October 2007.

Contributed/Invited Presentations

1. A Novel Algorithm for MALDI-TOF MS Data Processing Using Mathematical Tools. Spring Meeting of the Eastern North American Region of the International Biometric Society (ENAR), Austin, TX, Mar 19-22, 2005. CHEN S, HONG D, Shyr Y. 2. MALDI-TOF MS data processing using splines, wavelets, and clustering techniques. International Conference on the Interactions between Wavelets and Splines, University of Georgia, Athens, Georgia, May 16--19, 2005. CHEN S, HONG D, Shyr Y.

3. MALDI-TOF MS Data Processing by Feedback Concept. Workshop on Mathematical Tools and Statistical Techniques for Quantitative Medical Data Analysis, at ETSU, Johnson City, TN October 13-14, 2005 CHEN S, HONG D, Shyr Y.

4. Survival Analysis Based on MALDI-TOF MS Protein Profiles. 2005 Fall Southeast Section American Mathematics Society Meeting, East Tennessee State University, Johnson City, Tennessee. October 15-16, 2005 CHEN S, HONG D, Shyr Y.

5. Machine Learning algorithms: SVM, Beysian Network, and Random Forrest and their application in high-dimensional biomedical study for cancer research. Vanderbilt Ingram Cancer Center. Nashville, TN.

6. Quantification and Classification of Mass Spectrometry Data by Kernel Methods Spring Meeting of the Eastern North American Region of the International Biometric Society (ENAR), Atlanta, GA, Mar 10-14, 2007. CHEN S, HONG D, Shyr Y.

7. QA/QC and Reproducibility Analysis of Mass Spectrometry Data NSF Workshop on Quantitative Omics Data Analysis, Nov 1-2, 2007 CHEN S


1. Mass Spectrometry Data Preprocessing Using Mathematical and Statistical Techniques. Ming Li, Shuo Chen, Huiming Li, Baogang J. Xu, Don Hong, Dean Billheimer, Yu Shyr ,Robert Coffey, David Carbone. 13th SPORE Investigator’s Workshop, Washington, D.C. July 9-12 2005, Sponsored by NCI and NIH.

2. A Comprehensive MALDI-TOF MS Data Preprocessing Method Using Feedback Concept. Spring Meeting of the Eastern North American Region of the International Biometric Society (ENAR), Tampa, FL, Mar 19-22, 2006. CHEN S, Billheimer D, Li M, Li H, Hong D, Shyr Y.


The International Biometric Society

Institute of Mathematical Statistics

American Association for Cancer Research

Editorial Board Member in international journal "Journal of Wavelet Theory and Applications (JWTA)"
Topic revision: r10 - 11 Nov 2007, ShuoChen

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